Quantitative nanoscale studies of membranes and membrane-proteins using fluorescent microscopy.

Our lab at the University of Copenhagen is developing disruptive technologies to study study the pharmacology and biophysical properties of membrane proteins on the nanoscale using fluorescence microscopy. Membrane proteins are one of the most important classes of proteins in biology comprising more than 60% of existing pharmaceutical targets. Our current work focuses on two ubiquitous families of transmembrane proteins, G protein coupled receptors and Transporters .

The exciting problems we are investigating are situated at the interface of biology, physics and nanotechnology, and to address them experimentally we have assembled a dynamic, interdisciplinary, group of top-tier biophysicists, biochemists, molecular and cellular biologists, and nanotechnologists.

Research keywords: Nanoscale pharmacology; Membrane protein biophysics; G protein coupled receptors; Primary and secondary active transporters.